PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	MOB1B	CTRPv2	pan-cancer	AAC	-0.11	0.006
mRNA	ILK	CTRPv2	pan-cancer	AAC	-0.11	0.006
mRNA	EFNB2	FIMM	pan-cancer	AAC	-0.57	0.006
mRNA	BTG2	gCSI	pan-cancer	AAC	0.2	0.006
mRNA	MAN2A2	gCSI	pan-cancer	AAC	-0.17	0.006
mRNA	DTX4	gCSI	pan-cancer	AAC	0.18	0.006
mRNA	KIAA0922	CTRPv2	pan-cancer	AAC	0.12	0.006
mRNA	PSMB3	GDSC1000	pan-cancer	AAC	0.09	0.006
mRNA	HIST3H2A	CTRPv2	pan-cancer	AAC	-0.1	0.006
mRNA	WDR45B	CTRPv2	pan-cancer	AAC	-0.11	0.006