PharmacoDB

Sources

Names Used

GDC0941

gdc0941

Pictilisib

GDC-0941

PharmacoGx

GDC-0941

Database	Identifier
Smiles:	CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
Inchikey:	LHNIIDJUOCFXAP-UHFFFAOYSA-N
Pubchem:	17755052

Database

Identifier

Smiles:

CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

Inchikey:

LHNIIDJUOCFXAP-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to GDC-0941

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TUBD1	GDSC1000	pan-cancer	AAC	0.094	0.005
mRNA	BTG3	GDSC1000	pan-cancer	AAC	-0.093	0.005
mRNA	SPINK8	CTRPv2	pan-cancer	AAC	0.11	0.005
mRNA	PRKD1	GDSC1000	pan-cancer	AAC	-0.11	0.005
mRNA	STX3	GDSC1000	pan-cancer	AAC	-0.11	0.005
mRNA	CDIP1	gCSI	pan-cancer	AAC	-0.17	0.005
mRNA	MIER3	gCSI	pan-cancer	AAC	0.16	0.005
mRNA	MLANA	GDSC1000	pan-cancer	AAC	-0.12	0.005
mRNA	HGS	CTRPv2	pan-cancer	AAC	-0.1	0.005
mRNA	CES3	CTRPv2	pan-cancer	AAC	-0.11	0.005