PharmacoDB

Sources

Names Used

Nutlin-3

Nutlin 3a

nutlin-3

PharmacoGx

Nutlin-3

Database	Identifier
Smiles:	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey:	BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem:	216345

Database

Identifier

Smiles:

CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Inchikey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to Nutlin-3

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	TARBP2	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	RMDN2	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	FZD4	CCLE	pan-cancer	AAC	0.16	0.002
mRNA	ZMAT3	CCLE	pan-cancer	AAC	0.16	0.002
mRNA	YOD1	CCLE	pan-cancer	AAC	-0.15	0.002
mRNA	MFSD5	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	POGLUT1	CCLE	pan-cancer	AAC	0.16	0.002
mRNA	HSD17B14	CCLE	pan-cancer	AAC	0.15	0.002
mRNA	ADCY7	CCLE	pan-cancer	AAC	-0.15	0.002
mRNA	SLC39A6	CCLE	pan-cancer	AAC	0.15	0.002