PharmacoDB

Sources

Names Used

Nutlin-3

Nutlin 3a

nutlin-3

PharmacoGx

Nutlin-3

Database	Identifier
Smiles:	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey:	BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem:	216345

Database

Identifier

Smiles:

CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Inchikey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to Nutlin-3

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	ZW10	CTRPv2	pan-cancer	AAC	-0.17	5e-07
mRNA	FAM72B	CTRPv2	pan-cancer	AAC	-0.17	2e-05
mRNA	RHOBTB3	CTRPv2	pan-cancer	AAC	-0.17	1e-06
mRNA	ROMO1	CTRPv2	pan-cancer	AAC	-0.17	5e-07
mRNA	MANBAL	CTRPv2	pan-cancer	AAC	-0.17	0.0001
mRNA	PDZD11	CTRPv2	pan-cancer	AAC	-0.17	7e-06
mRNA	MET	CCLE	pan-cancer	AAC	-0.17	0.005
mRNA	KHDC1	CTRPv2	pan-cancer	AAC	-0.17	6e-06
mRNA	TNFRSF12A	CTRPv2	pan-cancer	AAC	-0.17	6e-05
mRNA	PSMA7	CTRPv2	pan-cancer	AAC	-0.17	2e-06