PharmacoDB

Sources

Names Used

Nutlin-3

Nutlin 3a

nutlin-3

PharmacoGx

Nutlin-3

Database	Identifier
Smiles:	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey:	BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem:	216345

Database

Identifier

Smiles:

CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Inchikey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to Nutlin-3

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	EVI2A	CTRPv2	pan-cancer	AAC	0.11	0.006
mRNA	PITX2	CCLE	pan-cancer	AAC	-0.14	0.006
mRNA	UPF3B	CTRPv2	pan-cancer	AAC	-0.094	0.006
mRNA	INPP5D	CTRPv2	pan-cancer	AAC	0.13	0.006
mRNA	PSMD14	CTRPv2	pan-cancer	AAC	-0.096	0.006
mRNA	NBPF19	CTRPv2	pan-cancer	AAC	-0.095	0.006
mRNA	CTD-2583A14.10	CTRPv2	pan-cancer	AAC	-0.094	0.006
mRNA	DOPEY1	CCLE	pan-cancer	AAC	-0.13	0.006
mRNA	ZNF285	CTRPv2	pan-cancer	AAC	-0.096	0.006
mRNA	MED22	CTRPv2	pan-cancer	AAC	-0.093	0.006