1. Home/
  2. Compounds/
  3. Nutlin-3

Nutlin-3

Synonyms

SourcesNames Used
CCLENutlin-3
GRAYNutlin 3a
CTRPv2nutlin-3
PharmacoGx Nutlin-3

External IDs

DatabaseIdentifier
Smiles: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey: BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem: 216345

Annotated Targets

MDM2, TP53

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to Nutlin-3


Feature TypeStandardized
Nominal ANOVA
mRNA MTCH1 CTRPv2 pan-cancer AAC -0.1 0.006
mRNA ANKRD42 CTRPv2 pan-cancer AAC -0.096 0.006
mRNA CCDC159 CTRPv2 pan-cancer AAC 0.099 0.006
mRNA TIFA CTRPv2 pan-cancer AAC 0.1 0.006
mRNA RPS6KB2 CTRPv2 pan-cancer AAC -0.096 0.006
mRNA LRRC66 CTRPv2 pan-cancer AAC 0.098 0.006
mRNA NME4 CTRPv2 pan-cancer AAC 0.098 0.006
mRNA TINF2 CCLE pan-cancer AAC 0.13 0.006
mRNA MYO5C CTRPv2 pan-cancer AAC 0.11 0.006
mRNA EFNA4 CTRPv2 pan-cancer AAC 0.1 0.006
Download CSV