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Nutlin-3

Synonyms

SourcesNames Used
CCLENutlin-3
GRAYNutlin 3a
CTRPv2nutlin-3
PharmacoGx Nutlin-3

External IDs

DatabaseIdentifier
Smiles: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey: BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem: 216345

Annotated Targets

MDM2, TP53

FDA Approval Status

Not Approved
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Top molecular features associated with response to Nutlin-3


Feature TypeStandardized
Nominal ANOVA
mRNA SVOPL CTRPv2 pan-cancer AAC -0.093 0.006
mRNA ERICH2 CTRPv2 pan-cancer AAC 0.093 0.006
mRNA COL11A1 CTRPv2 pan-cancer AAC 0.095 0.006
mRNA MGST1 CTRPv2 pan-cancer AAC -0.1 0.006
mRNA C19orf33 CTRPv2 pan-cancer AAC -0.12 0.006
mRNA ATP6V1E1 CTRPv2 pan-cancer AAC -0.1 0.006
mRNA PIANP CTRPv2 pan-cancer AAC 0.12 0.006
mRNA PSD4 CTRPv2 pan-cancer AAC 0.12 0.006
mRNA PDDC1 CCLE pan-cancer AAC -0.13 0.006
mRNA NYNRIN CTRPv2 pan-cancer AAC 0.096 0.006
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