PharmacoDB

Sources

Names Used

Nutlin-3

Nutlin 3a

nutlin-3

PharmacoGx

Nutlin-3

Database	Identifier
Smiles:	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey:	BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem:	216345

Database

Identifier

Smiles:

CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Inchikey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to Nutlin-3

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	HRH2	CTRPv2	pan-cancer	AAC	0.15	3e-05
mRNA	GMIP	CTRPv2	pan-cancer	AAC	0.19	3e-05
mRNA	C18orf32	CTRPv2	pan-cancer	AAC	0.15	3e-05
mRNA	TTI1	CTRPv2	pan-cancer	AAC	-0.14	3e-05
mRNA	LGALS9	CTRPv2	pan-cancer	AAC	0.16	3e-05
mRNA	DEPDC1	CTRPv2	pan-cancer	AAC	-0.15	3e-05
mRNA	C19orf45	CTRPv2	pan-cancer	AAC	0.15	3e-05
mRNA	YIPF5	CTRPv2	pan-cancer	AAC	-0.17	3e-05
mRNA	GPT	CTRPv2	pan-cancer	AAC	0.14	3e-05
mRNA	BAHCC1	CTRPv2	pan-cancer	AAC	0.15	3e-05