PharmacoDB

Sources

Names Used

Nutlin-3

Nutlin 3a

nutlin-3

PharmacoGx

Nutlin-3

Database	Identifier
Smiles:	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey:	BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem:	216345

Database

Identifier

Smiles:

CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Inchikey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to Nutlin-3

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	PAAF1	CTRPv2	pan-cancer	AAC	-0.15	2e-05
mRNA	TPT1	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	CACNB3	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	ZBED3	CTRPv2	pan-cancer	AAC	0.16	2e-05
mRNA	CECR6	CTRPv2	pan-cancer	AAC	0.14	2e-05
mRNA	KCNN2	CTRPv2	pan-cancer	AAC	0.15	2e-05
mRNA	TMED5	CTRPv2	pan-cancer	AAC	-0.15	2e-05
mRNA	FAM72B	CTRPv2	pan-cancer	AAC	-0.17	2e-05
mRNA	TSC22D2	CTRPv2	pan-cancer	AAC	-0.15	2e-05
mRNA	CAB39	CTRPv2	pan-cancer	AAC	-0.15	2e-05