PharmacoDB

Sources

Names Used

Nutlin-3

Nutlin 3a

nutlin-3

PharmacoGx

Nutlin-3

Database	Identifier
Smiles:	CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
Inchikey:	BDUHCSBCVGXTJM-UHFFFAOYSA-N
Pubchem:	216345

Database

Identifier

Smiles:

CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl

Inchikey:

BDUHCSBCVGXTJM-UHFFFAOYSA-N

Pubchem:

Top molecular features associated with response to Nutlin-3

Feature Type	Gene	Dataset	Tissue	Stat	Standardized Coefficient	Nominal ANOVA p-value
mRNA	RP11-156P1.2	CTRPv2	pan-cancer	AAC	-0.16	1e-05
mRNA	CYFIP2	CTRPv2	pan-cancer	AAC	0.18	1e-05
mRNA	MTMR4	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	GAMT	CTRPv2	pan-cancer	AAC	0.16	1e-05
mRNA	CXorf56	CTRPv2	pan-cancer	AAC	-0.15	1e-05
mRNA	TTLL6	CTRPv2	pan-cancer	AAC	0.15	1e-05
mRNA	COPB2	CTRPv2	pan-cancer	AAC	-0.16	1e-05
mRNA	RPL29	CTRPv2	pan-cancer	AAC	0.17	1e-05
mRNA	PPIL1	CTRPv2	pan-cancer	AAC	-0.15	1e-05
mRNA	MPG	CTRPv2	pan-cancer	AAC	0.15	1e-05