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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA CYP17A1 CTRPv2 pan-cancer AAC 0.22 1e-10
mRNA DAAM2 GDSC1000 pan-cancer AAC 0.26 1e-10
mRNA MBP CTRPv2 pan-cancer AAC 0.26 1e-10
mRNA FMN1 CCLE pan-cancer AAC 0.3 1e-10
mRNA SNX10 CTRPv2 pan-cancer AAC 0.25 1e-10
mRNA PHLDA3 CTRPv2 pan-cancer AAC 0.25 1e-10
mRNA SSH1 CTRPv2 pan-cancer AAC 0.29 1e-10
mRNA EXTL1 CTRPv2 pan-cancer AAC 0.25 1e-10
mRNA SYNM CTRPv2 pan-cancer AAC 0.25 2e-10
mRNA TYR CCLE pan-cancer AAC 0.36 2e-10
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