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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA ACP5 CTRPv2 pan-cancer AAC 0.34 1e-17
mRNA TRIM51 GDSC1000 pan-cancer AAC 0.35 1e-17
mRNA GAPDHS GDSC1000 pan-cancer AAC 0.28 2e-17
mRNA RXRG CCLE pan-cancer AAC 0.49 2e-17
mRNA RP11-290H9.2 CTRPv2 pan-cancer AAC 0.34 2e-17
mRNA GAPDHS CCLE pan-cancer AAC 0.37 3e-17
mRNA SRPX CTRPv2 pan-cancer AAC 0.36 6e-17
mRNA CPN1 GDSC1000 pan-cancer AAC 0.33 2e-16
mRNA FMN1 CTRPv2 pan-cancer AAC 0.33 4e-16
mRNA ROPN1 CTRPv2 pan-cancer AAC 0.33 5e-16
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