1. Home/
  2. Compounds/
  3. PLX4720

PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA GJB1 CCLE pan-cancer AAC 0.26 1e-07
mRNA C3orf67 CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA FAM167B CCLE pan-cancer AAC 0.28 1e-07
mRNA SLC20A1 CTRPv2 pan-cancer AAC 0.19 1e-07
mRNA VIP CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA C1QTNF3 CTRPv2 pan-cancer AAC 0.18 2e-07
mRNA PTPRZ1 CTRPv2 pan-cancer AAC 0.19 2e-07
mRNA PAX3 GDSC1000 pan-cancer AAC 0.19 2e-07
mRNA S100A1 CCLE pan-cancer AAC 0.29 2e-07
mRNA BIRC7 CTRPv2 pan-cancer AAC 0.19 2e-07
Download CSV