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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA DUSP10 CTRPv2 pan-cancer AAC 0.2 6e-08
mRNA ATP6V1B2 CTRPv2 pan-cancer AAC 0.22 6e-08
mRNA RLBP1 CCLE pan-cancer AAC 0.25 7e-08
mRNA ACP5 GDSC1000 pan-cancer AAC 0.21 7e-08
mRNA PLEKHA4 CTRPv2 pan-cancer AAC 0.21 7e-08
mRNA RHOJ CCLE pan-cancer AAC 0.31 7e-08
mRNA GYG2 CTRPv2 pan-cancer AAC 0.2 7e-08
mRNA MFSD12 CTRPv2 pan-cancer AAC 0.24 7e-08
mRNA PRSS33 CCLE pan-cancer AAC 0.23 7e-08
mRNA UBL3 CTRPv2 pan-cancer AAC 0.21 8e-08
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