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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA BMS1 GDSC1000 pan-cancer AAC -0.089 0.004
mRNA SLC8A2 GDSC1000 pan-cancer AAC -0.089 0.004
mRNA CCDC66 CCLE pan-cancer AAC -0.15 0.004
mRNA ZNF567 GDSC1000 pan-cancer AAC -0.092 0.004
mRNA AKAP8 GDSC1000 pan-cancer AAC -0.098 0.004
mRNA BCDIN3D CTRPv2 pan-cancer AAC -0.11 0.004
mRNA HMGN3 CCLE pan-cancer AAC -0.13 0.004
mRNA LGALS3BP GDSC1000 pan-cancer AAC 0.11 0.004
mRNA LOXL3 CCLE pan-cancer AAC 0.16 0.004
mRNA MMGT1 GDSC1000 pan-cancer AAC -0.087 0.004
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