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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA TRIM63 CCLE pan-cancer AAC 0.29 4e-08
mRNA ITGA9 CTRPv2 pan-cancer AAC 0.2 5e-08
mRNA C5orf47 CTRPv2 pan-cancer AAC 0.19 5e-08
mRNA LGI3 CCLE pan-cancer AAC 0.25 5e-08
mRNA TREH CTRPv2 pan-cancer AAC 0.21 5e-08
mRNA FBXO7 CTRPv2 pan-cancer AAC 0.23 5e-08
mRNA IL1RAPL1 CTRPv2 pan-cancer AAC 0.2 6e-08
mRNA VGF GDSC1000 pan-cancer AAC 0.18 6e-08
mRNA TBC1D16 GDSC1000 pan-cancer AAC 0.2 6e-08
mRNA UCN2 CTRPv2 pan-cancer AAC 0.22 6e-08
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