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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA NRP2 CTRPv2 pan-cancer AAC 0.22 2e-08
mRNA PHLDA2 CTRPv2 pan-cancer AAC 0.22 2e-08
mRNA ARAP3 CTRPv2 pan-cancer AAC 0.21 2e-08
mRNA SH3TC2 CTRPv2 pan-cancer AAC 0.23 2e-08
mRNA C16orf82 CTRPv2 pan-cancer AAC 0.19 2e-08
mRNA PAX3 CTRPv2 pan-cancer AAC 0.24 2e-08
mRNA ARG1 CCLE pan-cancer AAC 0.25 2e-08
mRNA CDH19 CTRPv2 pan-cancer AAC 0.22 2e-08
mRNA KRT82 CTRPv2 pan-cancer AAC 0.19 2e-08
mRNA GAPDHS CTRPv2 pan-cancer AAC 0.19 2e-08
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