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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA CST3 CTRPv2 pan-cancer AAC 0.21 4e-09
mRNA FCGR3A CTRPv2 pan-cancer AAC 0.2 4e-09
mRNA ITIH5 CTRPv2 pan-cancer AAC 0.21 5e-09
mRNA GABRA1 CTRPv2 pan-cancer AAC 0.2 5e-09
mRNA ACP5 CCLE pan-cancer AAC 0.3 5e-09
mRNA CYP3A7 CTRPv2 pan-cancer AAC 0.2 6e-09
mRNA CYP27A1 CCLE pan-cancer AAC 0.31 6e-09
mRNA FRMD5 CTRPv2 pan-cancer AAC 0.23 6e-09
mRNA ALDH1A3 CTRPv2 pan-cancer AAC 0.21 7e-09
mRNA SERPINI1 CTRPv2 pan-cancer AAC 0.2 7e-09
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