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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA TRPV4 CTRPv2 pan-cancer AAC 0.22 4e-10
mRNA TRIM63 GDSC1000 pan-cancer AAC 0.25 4e-10
mRNA FGL2 CTRPv2 pan-cancer AAC 0.21 4e-10
mRNA S100B GDSC1000 pan-cancer AAC 0.28 4e-10
mRNA KLF9 CTRPv2 pan-cancer AAC 0.25 4e-10
mRNA TYR CTRPv2 pan-cancer AAC 0.24 4e-10
mRNA PRSS33 GDSC1000 pan-cancer AAC 0.19 4e-10
mRNA PLA1A CCLE pan-cancer AAC 0.31 4e-10
mRNA MMP8 CCLE pan-cancer AAC 0.4 5e-10
mRNA CD200 CTRPv2 pan-cancer AAC 0.24 5e-10
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