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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SLC45A2 CCLE pan-cancer AAC 0.35 9e-12
mRNA BCL2A1 GDSC1000 pan-cancer AAC 0.24 1e-11
mRNA ZNF697 CTRPv2 pan-cancer AAC 0.29 1e-11
mRNA MCAM CTRPv2 pan-cancer AAC 0.27 1e-11
mRNA NPAS1 CTRPv2 pan-cancer AAC 0.24 2e-11
mRNA FAM167B GDSC1000 pan-cancer AAC 0.24 2e-11
mRNA CYP7B1 CTRPv2 pan-cancer AAC 0.24 2e-11
mRNA TYR GDSC1000 pan-cancer AAC 0.29 2e-11
mRNA SHC4 CCLE pan-cancer AAC 0.39 2e-11
mRNA BIRC7 GDSC1000 pan-cancer AAC 0.22 3e-11
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