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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA S100B CTRPv2 pan-cancer AAC 0.27 1e-12
mRNA ZMAT3 CTRPv2 pan-cancer AAC 0.26 2e-12
mRNA MMP16 CTRPv2 pan-cancer AAC 0.26 2e-12
mRNA MLANA GDSC1000 pan-cancer AAC 0.29 2e-12
mRNA SLC24A5 GDSC1000 pan-cancer AAC 0.27 3e-12
mRNA MLANA CCLE pan-cancer AAC 0.38 3e-12
mRNA CPN1 CCLE pan-cancer AAC 0.4 3e-12
mRNA FNTB CTRPv2 pan-cancer AAC 0.3 3e-12
mRNA APOC4 CTRPv2 pan-cancer AAC 0.24 7e-12
mRNA DCT CCLE pan-cancer AAC 0.42 8e-12
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