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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SLC45A2 GDSC1000 pan-cancer AAC 0.29 1e-13
mRNA UCN2 GDSC1000 pan-cancer AAC 0.26 2e-13
mRNA SNRPB2 CTRPv2 pan-cancer AAC 0.27 3e-13
mRNA S100A1 CTRPv2 pan-cancer AAC 0.28 4e-13
mRNA LINC01314 CTRPv2 pan-cancer AAC 0.25 6e-13
mRNA VGF CCLE pan-cancer AAC 0.33 6e-13
mRNA ROPN1B CTRPv2 pan-cancer AAC 0.29 7e-13
mRNA IFNGR2 CTRPv2 pan-cancer AAC 0.26 1e-12
mRNA PLP1 CTRPv2 pan-cancer AAC 0.31 1e-12
mRNA S100B CCLE pan-cancer AAC 0.51 1e-12
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