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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SH3BP4 CCLE pan-cancer AAC 0.18 0.004
mRNA ERN1 CTRPv2 pan-cancer AAC -0.1 0.004
mRNA VAMP5 GDSC1000 pan-cancer AAC 0.095 0.004
mRNA ESM1 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA BACH1 CTRPv2 pan-cancer AAC 0.1 0.004
mRNA SGCD GDSC1000 pan-cancer AAC 0.11 0.004
mRNA APOLD1 GDSC1000 pan-cancer AAC 0.089 0.004
mRNA ENTPD6 CTRPv2 pan-cancer AAC 0.11 0.004
mRNA TMEM53 CCLE pan-cancer AAC 0.13 0.004
mRNA HCG27 CCLE pan-cancer AAC -0.15 0.004
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