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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA CD63 CTRPv2 pan-cancer AAC 0.26 7e-10
mRNA CCL25 CTRPv2 pan-cancer AAC 0.21 9e-10
mRNA ANKS1A CTRPv2 pan-cancer AAC 0.23 9e-10
mRNA CACNA1S CTRPv2 pan-cancer AAC 0.21 9e-10
mRNA ASCL5 CTRPv2 pan-cancer AAC 0.21 9e-10
mRNA MRGPRX4 CTRPv2 pan-cancer AAC 0.26 1e-09
mRNA WDR63 CTRPv2 pan-cancer AAC 0.22 1e-09
mRNA PTCHD4 CTRPv2 pan-cancer AAC 0.23 1e-09
mRNA SOX10 CCLE pan-cancer AAC 0.45 1e-09
mRNA SFTPC CTRPv2 pan-cancer AAC 0.21 2e-09
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