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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SERPINE2 CTRPv2 pan-cancer AAC 0.3 2e-14
mRNA SLC23A2 CTRPv2 pan-cancer AAC 0.29 2e-14
mRNA PLP1 GDSC1000 pan-cancer AAC 0.36 2e-14
mRNA FAM210A CTRPv2 pan-cancer AAC 0.29 2e-14
mRNA LAMA4 CTRPv2 pan-cancer AAC 0.3 3e-14
mRNA TRIM51 CTRPv2 pan-cancer AAC 0.3 3e-14
mRNA GAS7 CTRPv2 pan-cancer AAC 0.31 5e-14
mRNA COL9A3 CTRPv2 pan-cancer AAC 0.3 5e-14
mRNA WWTR1 CTRPv2 pan-cancer AAC 0.31 7e-14
mRNA PLP1 CCLE pan-cancer AAC 0.56 8e-14
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