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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA FAM189A1 CTRPv2 pan-cancer AAC 0.22 3e-11
mRNA TRIB2 CTRPv2 pan-cancer AAC 0.27 3e-11
mRNA FKBP1A CTRPv2 pan-cancer AAC 0.24 4e-11
mRNA AFAP1L1 CTRPv2 pan-cancer AAC 0.25 6e-11
mRNA METRN CTRPv2 pan-cancer AAC 0.25 7e-11
mRNA AP1S2 CTRPv2 pan-cancer AAC 0.27 8e-11
mRNA MMP17 CTRPv2 pan-cancer AAC 0.25 8e-11
mRNA PLXNB3 CTRPv2 pan-cancer AAC 0.26 9e-11
mRNA TLR8 CCLE pan-cancer AAC 0.27 1e-10
mRNA CSPG4 CTRPv2 pan-cancer AAC 0.27 1e-10
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