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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SPRY4 GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA SHTN1 CCLE pan-cancer AAC 0.28 6e-06
mRNA PCDHGB2 CTRPv2 pan-cancer AAC 0.2 6e-06
mRNA PCDHGA8 CTRPv2 pan-cancer AAC 0.2 6e-06
mRNA TBC1D4 GDSC1000 pan-cancer AAC 0.14 6e-06
mRNA CNIH3 CTRPv2 pan-cancer AAC 0.16 6e-06
mRNA SOX5 CTRPv2 pan-cancer AAC 0.17 6e-06
mRNA TSPAN10 GDSC1000 pan-cancer AAC 0.15 6e-06
mRNA PCDHGB3 CTRPv2 pan-cancer AAC 0.2 6e-06
mRNA SERPINA3 CTRPv2 pan-cancer AAC 0.15 6e-06
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