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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SOX10 GDSC1000 pan-cancer AAC 0.19 5e-06
mRNA C19orf71 CTRPv2 pan-cancer AAC 0.2 5e-06
mRNA LAMA1 CCLE pan-cancer AAC 0.22 5e-06
mRNA PNPLA3 CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA NID1 CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA CCDC6 GDSC1000 pan-cancer AAC -0.15 6e-06
mRNA PCDHGA5 CTRPv2 pan-cancer AAC 0.2 6e-06
mRNA ABR GDSC1000 pan-cancer AAC 0.14 6e-06
mRNA ATP1A1 CCLE pan-cancer AAC 0.22 6e-06
mRNA JADE1 CCLE pan-cancer AAC -0.23 6e-06
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