1. Home/
  2. Compounds/
  3. PLX4720

PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA PCDHGB6 CTRPv2 pan-cancer AAC 0.2 5e-06
mRNA PCDHGA6 CTRPv2 pan-cancer AAC 0.2 5e-06
mRNA PMP2 CTRPv2 pan-cancer AAC 0.16 5e-06
mRNA ZNF827 CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA GDF15 CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA EDNRB GDSC1000 pan-cancer AAC 0.19 5e-06
mRNA TMTC2 CCLE pan-cancer AAC 0.23 5e-06
mRNA CYP17A1 GDSC1000 pan-cancer AAC 0.13 5e-06
mRNA GHR CTRPv2 pan-cancer AAC 0.17 5e-06
mRNA ST8SIA1 CTRPv2 pan-cancer AAC 0.17 5e-06
Download CSV