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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA PCDHGA7 CTRPv2 pan-cancer AAC 0.2 3e-06
mRNA KRT27 GDSC1000 pan-cancer AAC 0.14 3e-06
mRNA ZNF106 CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA TNC CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA DAAM2 CCLE pan-cancer AAC 0.26 3e-06
mRNA TTLL4 GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA A2M GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA S100A1 GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA SOX6 CTRPv2 pan-cancer AAC 0.17 4e-06
mRNA UCN2 CCLE pan-cancer AAC 0.23 4e-06
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