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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA CST1 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA DNASE2B CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA TSNAX CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA SPRY2 CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA P2RX6 CTRPv2 pan-cancer AAC 0.17 3e-06
mRNA ARHGAP31 CTRPv2 pan-cancer AAC 0.2 3e-06
mRNA ENTHD1 CCLE pan-cancer AAC 0.22 3e-06
mRNA BCAN CCLE pan-cancer AAC 0.2 3e-06
mRNA CACHD1 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA WDR63 GDSC1000 pan-cancer AAC 0.14 3e-06
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