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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA EDNRB CCLE pan-cancer AAC 0.27 2e-06
mRNA PYGB CCLE pan-cancer AAC 0.24 2e-06
mRNA MFSD12 GDSC1000 pan-cancer AAC 0.18 2e-06
mRNA SLC5A4 CCLE pan-cancer AAC 0.22 3e-06
mRNA ASB18 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA CPLX3 CTRPv2 pan-cancer AAC 0.16 3e-06
mRNA FARP2 CTRPv2 pan-cancer AAC 0.19 3e-06
mRNA PCDHGA9 CTRPv2 pan-cancer AAC 0.21 3e-06
mRNA APOBEC3C CTRPv2 pan-cancer AAC 0.18 3e-06
mRNA TRPM1 CCLE pan-cancer AAC 0.22 3e-06
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