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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA APOC2 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA SCML4 CTRPv2 pan-cancer AAC 0.17 2e-06
mRNA KIF3C CTRPv2 pan-cancer AAC 0.19 2e-06
mRNA KIAA1549L CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA ASB4 CCLE pan-cancer AAC 0.21 2e-06
mRNA SASH1 CTRPv2 pan-cancer AAC 0.2 2e-06
mRNA TMEM17 CCLE pan-cancer AAC 0.25 2e-06
mRNA GPM6B CCLE pan-cancer AAC 0.25 2e-06
mRNA APP CTRPv2 pan-cancer AAC 0.19 2e-06
mRNA ITGA10 CTRPv2 pan-cancer AAC 0.16 2e-06
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