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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA APOD CTRPv2 pan-cancer AAC 0.28 5e-16
mRNA SPRED1 CTRPv2 pan-cancer AAC 0.33 8e-16
mRNA TRIM51 CCLE pan-cancer AAC 0.5 1e-15
mRNA SOX10 CTRPv2 pan-cancer AAC 0.44 3e-15
mRNA SDC3 CTRPv2 pan-cancer AAC 0.37 3e-15
mRNA EGR3 CTRPv2 pan-cancer AAC 0.29 1e-14
mRNA SH2B3 CTRPv2 pan-cancer AAC 0.31 1e-14
mRNA PRNP CTRPv2 pan-cancer AAC 0.3 1e-14
mRNA DCT GDSC1000 pan-cancer AAC 0.31 2e-14
mRNA ROPN1 CCLE pan-cancer AAC 0.47 2e-14
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