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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA PCDHGC3 CTRPv2 pan-cancer AAC 0.21 1e-06
mRNA FNTB CCLE pan-cancer AAC 0.24 1e-06
mRNA EDA2R CTRPv2 pan-cancer AAC 0.19 1e-06
mRNA SEC14L4 CTRPv2 pan-cancer AAC 0.17 1e-06
mRNA SLC38A1 CCLE pan-cancer AAC -0.25 1e-06
mRNA ARHGEF11 CTRPv2 pan-cancer AAC 0.2 1e-06
mRNA AGAP3 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA PRKCDBP CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA CNTNAP3B CTRPv2 pan-cancer AAC 0.17 1e-06
mRNA KRTAP13-2 CTRPv2 pan-cancer AAC 0.17 1e-06
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