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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA ST3GAL4 CTRPv2 pan-cancer AAC 0.21 9e-07
mRNA PMEL GDSC1000 pan-cancer AAC 0.19 9e-07
mRNA LRGUK GDSC1000 pan-cancer AAC 0.17 1e-06
mRNA MS4A4A CCLE pan-cancer AAC 0.22 1e-06
mRNA EIF2AK4 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA METTL9 GDSC1000 pan-cancer AAC 0.15 1e-06
mRNA CHCHD6 GDSC1000 pan-cancer AAC 0.17 1e-06
mRNA SLAMF9 CTRPv2 pan-cancer AAC 0.18 1e-06
mRNA QDPR CTRPv2 pan-cancer AAC 0.2 1e-06
mRNA STKLD1 CTRPv2 pan-cancer AAC 0.18 1e-06
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