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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA ZNF697 CCLE pan-cancer AAC 0.27 7e-07
mRNA SLC4A3 CTRPv2 pan-cancer AAC 0.19 7e-07
mRNA IFT81 GDSC1000 pan-cancer AAC 0.17 8e-07
mRNA FXYD7 CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA STK32B CTRPv2 pan-cancer AAC 0.2 8e-07
mRNA GPR155 CTRPv2 pan-cancer AAC 0.17 8e-07
mRNA STRADB CTRPv2 pan-cancer AAC 0.18 8e-07
mRNA INPP5F CCLE pan-cancer AAC 0.28 8e-07
mRNA GKAP1 CCLE pan-cancer AAC -0.23 8e-07
mRNA FMNL2 CTRPv2 pan-cancer AAC 0.18 9e-07
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