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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA C1QC CTRPv2 pan-cancer AAC 0.17 5e-07
mRNA LGI3 CTRPv2 pan-cancer AAC 0.18 5e-07
mRNA CNP CTRPv2 pan-cancer AAC 0.21 6e-07
mRNA PLA1A GDSC1000 pan-cancer AAC 0.16 6e-07
mRNA PRDM7 GDSC1000 pan-cancer AAC 0.17 6e-07
mRNA SPRY4 CCLE pan-cancer AAC 0.25 6e-07
mRNA SLC35B2 CTRPv2 pan-cancer AAC 0.19 7e-07
mRNA CEMP1 CTRPv2 pan-cancer AAC 0.18 7e-07
mRNA MAG CTRPv2 pan-cancer AAC 0.18 7e-07
mRNA SHC4 GDSC1000 pan-cancer AAC 0.19 7e-07
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