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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SHISA4 CTRPv2 pan-cancer AAC 0.22 4e-07
mRNA LHFPL2 CTRPv2 pan-cancer AAC 0.2 4e-07
mRNA FGFBP2 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA HMCN1 CTRPv2 pan-cancer AAC 0.21 4e-07
mRNA ZDHHC19 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA GPNMB CTRPv2 pan-cancer AAC 0.22 5e-07
mRNA SVIL CTRPv2 pan-cancer AAC 0.19 5e-07
mRNA MYH10 CTRPv2 pan-cancer AAC 0.19 5e-07
mRNA OR2C3 GDSC1000 pan-cancer AAC 0.15 5e-07
mRNA IGSF11 CCLE pan-cancer AAC 0.25 5e-07
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