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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA COL19A1 CTRPv2 pan-cancer AAC 0.19 3e-07
mRNA GDF15 CCLE pan-cancer AAC 0.25 3e-07
mRNA BCAP29 CTRPv2 pan-cancer AAC 0.19 3e-07
mRNA RDH8 CTRPv2 pan-cancer AAC 0.17 3e-07
mRNA TCN1 CCLE pan-cancer AAC 0.22 4e-07
mRNA PFKFB4 CCLE pan-cancer AAC 0.27 4e-07
mRNA PTPRZ1 CCLE pan-cancer AAC 0.26 4e-07
mRNA CNPY1 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA APOC4-APOC2 CTRPv2 pan-cancer AAC 0.17 4e-07
mRNA HIVEP3 CTRPv2 pan-cancer AAC 0.19 4e-07
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