1. Home/
  2. Compounds/
  3. PLX4720

PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SLC35A3 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA GK2 GDSC1000 pan-cancer AAC -0.088 0.003
mRNA IPP GDSC1000 pan-cancer AAC 0.094 0.003
mRNA SSH1 CCLE pan-cancer AAC 0.16 0.003
mRNA MELTF GDSC1000 pan-cancer AAC 0.097 0.003
mRNA SHOX GDSC1000 pan-cancer AAC -0.09 0.003
mRNA BTBD3 CTRPv2 pan-cancer AAC 0.1 0.003
mRNA LRPAP1 CTRPv2 pan-cancer AAC 0.1 0.003
mRNA ARPC1B CTRPv2 pan-cancer AAC 0.11 0.003
mRNA CDCA8 CTRPv2 pan-cancer AAC -0.1 0.003
Download CSV