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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SHROOM3 GDSC1000 pan-cancer AAC -0.11 0.003
mRNA MIPEP GDSC1000 pan-cancer AAC 0.098 0.003
mRNA UPF2 CCLE pan-cancer AAC -0.15 0.003
mRNA GKAP1 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA RAB13 CTRPv2 pan-cancer AAC 0.12 0.003
mRNA CPEB2 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA NACC2 CTRPv2 pan-cancer AAC 0.12 0.003
mRNA CNTD1 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA FNBP4 CCLE pan-cancer AAC -0.14 0.003
mRNA FIBIN CTRPv2 pan-cancer AAC 0.1 0.003
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