1. Home/
  2. Compounds/
  3. PLX4720

PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
Dataset Select
Download Data as CSV

Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA ADGRG1 CCLE pan-cancer AAC 0.15 0.003
mRNA HSPB6 CTRPv2 pan-cancer AAC -0.11 0.003
mRNA TRPM8 GDSC1000 pan-cancer AAC 0.096 0.003
mRNA OSBPL6 CTRPv2 pan-cancer AAC 0.11 0.003
mRNA PAIP2B CTRPv2 pan-cancer AAC -0.11 0.003
mRNA ODF3L2 GDSC1000 pan-cancer AAC -0.089 0.003
mRNA ANTXR2 GDSC1000 pan-cancer AAC 0.094 0.003
mRNA ADGRV1 GDSC1000 pan-cancer AAC -0.1 0.003
mRNA STX17 CTRPv2 pan-cancer AAC -0.1 0.003
mRNA STAT5B CCLE pan-cancer AAC -0.16 0.003
Download CSV