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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA PREP CCLE pan-cancer AAC 0.14 0.002
mRNA WDR73 CCLE pan-cancer AAC 0.13 0.002
mRNA SPCS2 CTRPv2 pan-cancer AAC -0.1 0.002
mRNA CHTOP CTRPv2 pan-cancer AAC -0.11 0.002
mRNA RASAL3 CCLE pan-cancer AAC -0.21 0.002
mRNA PARM1 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA SRGAP2 GDSC1000 pan-cancer AAC 0.096 0.002
mRNA TMEM98 GDSC1000 pan-cancer AAC 0.1 0.002
mRNA ZC3H12C CTRPv2 pan-cancer AAC 0.11 0.002
mRNA AFF2 CCLE pan-cancer AAC -0.15 0.002
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