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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA ADAMTS9 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA FASLG CCLE pan-cancer AAC 0.14 0.002
mRNA ACVR1 CCLE pan-cancer AAC 0.17 0.002
mRNA MARCH8 GDSC1000 pan-cancer AAC -0.094 0.002
mRNA ATP1B3 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA IGF1 GDSC1000 pan-cancer AAC -0.096 0.002
mRNA MYL10 CCLE pan-cancer AAC 0.13 0.002
mRNA HTR7 CCLE pan-cancer AAC 0.14 0.002
mRNA FOXN3 GDSC1000 pan-cancer AAC -0.1 0.002
mRNA CHRM1 GDSC1000 pan-cancer AAC -0.095 0.002
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