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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA RAB38 CTRPv2 pan-cancer AAC 0.13 0.002
mRNA SORBS2 CTRPv2 pan-cancer AAC 0.11 0.002
mRNA TCF4 CCLE pan-cancer AAC -0.16 0.002
mRNA DUSP23 CCLE pan-cancer AAC 0.15 0.002
mRNA GHR GDSC1000 pan-cancer AAC 0.098 0.002
mRNA CST1 CCLE pan-cancer AAC 0.13 0.002
mRNA RUBCN CTRPv2 pan-cancer AAC -0.11 0.002
mRNA BEX5 CTRPv2 pan-cancer AAC -0.1 0.002
mRNA BARD1 CCLE pan-cancer AAC -0.14 0.002
mRNA CYTIP CCLE pan-cancer AAC -0.2 0.002
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