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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA ADM2 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA KIF3C GDSC1000 pan-cancer AAC 0.11 0.002
mRNA PROS1 CCLE pan-cancer AAC 0.15 0.002
mRNA NIN CTRPv2 pan-cancer AAC 0.11 0.002
mRNA KLC2 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA TRIM26 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA UHRF1BP1 CTRPv2 pan-cancer AAC -0.11 0.002
mRNA ARIH2OS CTRPv2 pan-cancer AAC -0.11 0.002
mRNA ASAP1 CTRPv2 pan-cancer AAC 0.12 0.002
mRNA WDR91 CTRPv2 pan-cancer AAC 0.12 0.002
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