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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA KCNN2 CCLE pan-cancer AAC 0.27 9e-09
mRNA RP1-317E23.6 CTRPv2 pan-cancer AAC 0.24 9e-09
mRNA KDR CTRPv2 pan-cancer AAC 0.2 1e-08
mRNA ROPN1 GDSC1000 pan-cancer AAC 0.22 1e-08
mRNA OR2A1 CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA FABP7 CCLE pan-cancer AAC 0.28 1e-08
mRNA LOXL3 CTRPv2 pan-cancer AAC 0.22 1e-08
mRNA LOXL4 CTRPv2 pan-cancer AAC 0.21 1e-08
mRNA GPC6 CTRPv2 pan-cancer AAC 0.21 2e-08
mRNA GRIP2 CTRPv2 pan-cancer AAC 0.2 2e-08
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