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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA SHROOM4 CTRPv2 pan-cancer AAC 0.23 3e-09
mRNA ITIH6 CTRPv2 pan-cancer AAC 0.21 4e-09
mRNA LINGO1 CTRPv2 pan-cancer AAC 0.22 4e-09
mRNA B4GALT6 CTRPv2 pan-cancer AAC 0.22 4e-09
mRNA CDRT15L2 CTRPv2 pan-cancer AAC 0.2 4e-09
mRNA HPS5 CTRPv2 pan-cancer AAC 0.24 4e-09
mRNA CH17-296N19.1 CTRPv2 pan-cancer AAC 0.21 4e-09
mRNA CYP3A7-CYP3A51P CTRPv2 pan-cancer AAC 0.2 4e-09
mRNA RHOJ CTRPv2 pan-cancer AAC 0.25 4e-09
mRNA GLB1L CTRPv2 pan-cancer AAC 0.21 4e-09
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