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PLX4720

Synonyms

SourcesNames Used
CCLE, GDSC1000PLX4720
CTRPv2PLX-4720
PharmacoGx PLX4720

External IDs

DatabaseIdentifier
Smiles: CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
Inchikey: YZDJQTHVDDOVHR-UHFFFAOYSA-N
Pubchem: 24180719

Annotated Targets

BRAF, KDR

FDA Approval Status

Not Approved
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Top molecular features associated with response to PLX4720


Feature TypeStandardized
Nominal ANOVA
mRNA CPN1 CTRPv2 pan-cancer AAC 0.25 2e-09
mRNA SLC27A3 CTRPv2 pan-cancer AAC 0.2 2e-09
mRNA IGSF8 CTRPv2 pan-cancer AAC 0.23 2e-09
mRNA C10orf90 CTRPv2 pan-cancer AAC 0.28 2e-09
mRNA PMEL CCLE pan-cancer AAC 0.31 2e-09
mRNA LRRK2 CCLE pan-cancer AAC 0.3 2e-09
mRNA C10orf90 GDSC1000 pan-cancer AAC 0.24 2e-09
mRNA FAM210B CTRPv2 pan-cancer AAC 0.23 2e-09
mRNA PLOD3 CTRPv2 pan-cancer AAC 0.26 3e-09
mRNA C10orf90 CCLE pan-cancer AAC 0.4 3e-09
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